Structural gene of pneumococcal protein
US5728387A · kind A · utility
17Cited by
2References
9Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Mar 17, 1994 |
| Grant date | Mar 17, 1998 |
| Priority date | — |
| Expiry date | Mar 17, 2014 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K2319/02
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A purified pneumococcal surface protein A (PspA) comprises a truncated form of the PspA protein which is immunoprotective and contains the protective epitopes of PspA. The PspA protein is soluble in physiologic solution and lacks at least the cell membrane anchor region of the whole protein. The protein is formed by insertion-duplication of mutagenesis of S. pneumoniae with pspA gene and expression of the truncated protein into the growth medium.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.