Patent · US Expired

Method of detecting variant nucleic acids using extension oligonucleotides which differ from each other at both a position corresponding to the variant nucleic acids and one or more additional positions

US5728530A · kind A · utility

1Cited by

0References

3Claims

0Family size

Assignee

Boehringer Mannheim GmbH · DE

Inventors

Stephan Rust · Munster, DE
Harald Funke · Munster, DE
Gerd Assmann · Munster, DE
Christoph Kessler · Munich, DE
Rudiger Rueger · Seeshaupt, DE

Key dates

Filing date	Mar 6, 1996
Grant date	Mar 17, 1998
Priority date	—
Expiry date	Mar 6, 2016

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC12Q1/6858
WIPO fieldBiotechnology
WIPO sectorChemistry

Abstract

Method of detecting nucleic acids whose nucleotide sequences differ from one another at a position X. The method uses a set of oligonucleotides where the nucleotides found at position X are complementary to a variant nucleic acids only at this position X. However, with respect to the position of another mismatch Y, the nucleotide sequences thereof differ from one another. The invention further addresses reagents for performing the methods as well as reagents and applications of the method.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.