Patent · US Expired

Production of .omega.-cyanocarboxamides from aliphatic .alpha.,.omega.-dinitriles using pseudomonas putida-derived biocatalysts

US5728556A · kind A · utility

2Cited by

9References

9Claims

0Family size

Assignee

E.I. DU PONT DE NEMOURS AND COMPANY · US

Inventors

Robert DiCosimo · Chadds Ford, US
Barry Stieglitz · Lansdowne, US
Robert D. Fallon · Elkton, US

Key dates

Filing date	Mar 14, 1996
Grant date	Mar 17, 1998
Priority date	—
Expiry date	Mar 14, 2016

Classification

Technology area (CPC Y)Emerging Cross-Sectional Technologies
CPC primaryY10S435/877
WIPO fieldBiotechnology
WIPO sectorChemistry

Abstract

Applicants have provided methods for obtaining aliphatic omega-cyanocaboximides of Formula I EQU NC--CH(R.sub.1)(CH).sub.n CH(R.sub.2)C(O)NH.sub.2 wherein n=1-8 and R.sub.1 or R.sub.2 are either H or CH.sub.3, from dinitriles of Formula II EQU NC--CH(R.sub.1)(CH).sub.n CH(R.sub.2)CN wherein n=1-8 and R.sub.1 or R.sub.2 are either H or CH.sub.3, using biocatalysts which have regioselective nitrile hydratase activity and which are derived from members of the bacterial species Pseudomonas putida.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.