Peptide of the structural phosphoprotein (pp 150) of human cytomegalovirus, and DNA encoding said peptide

US5728578A · kind A · utility

Assignee

• Behring Diagnostics GmbH · DE

Inventors

• Gerhard Jahn · Neunkirchen, DE
• Birgit-Christine Scholl · Uttenreuth, DE
• Michael Broker · Marburg, DE
• Michael Mach · Erlangen, DE
• Bernhard Fleckenstein · Wiesenthau, DE
• Bernd Traupe · Hamburg, DE

Key dates

• Filing date: Dec 1, 1993
• Grant date: Mar 17, 1998
• Expiry date: Dec 1, 2013

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C12N2710/16122
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The phosphorylated structural protein of molecular weight about 150 kd (pp 150) of human cytomegalovirus (HCMV) is highly immunogenic and is reliably recognised by human antisera. This protein can, after assignment and sequencing of the gene, be prepared, in whole or in immunogenic sections, by gene manipulation. Proteins of this type are suitable as reagents, for example in an ELISA, and as constituents of vaccines.