Patent · US Expired

Tricyclic carbamate compounds useful for inhibition of G-protein function and for treatment of proliferative diseases

US5728703A · kind A · utility

30Cited by
8References
16Claims
0Family size

Assignee

Inventors

Key dates

Filing dateMay 31, 1995
Grant dateMar 17, 1998
Priority date
Expiry dateMay 31, 2015

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D401/14
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

A method of inhibiting Ras function and therefore inhibiting cellular growth is disclosed. The method comprises the administration of a compound of Formula. 1.0 ##STR1## Also disclosed are novel compounds of the formulas: ##STR2## Also disclosed are processes for making 3-substituted compounds of the Formulas 1.1, 1.2 and 1.3. Further disclosed are novel compounds which are intermediates in the processes for making the 3-substituted compounds of Formulas 1.1, 1.2, and 1.3.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.