Octahydro-1H-pyrrolo3,2-g!and 2,3-g!isoquinoline derivatives
US5731322A · kind A · utility
2Cited by
1References
8Claims
0Family size
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Key dates
| Filing date | Apr 18, 1996 |
| Grant date | Mar 24, 1998 |
| Priority date | — |
| Expiry date | Apr 18, 2016 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P37/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Tricyclic derivatives of octahydroisoquinoline of formula (I), wherein n is zero or 1 and if n is zero, one of X or Y is NH, oxygen or sulphur, and the other is NH, CH or a R.sub.4 - or R.sub.5 -substituted carbon atom; if n is 1, then X and Y are both nitrogen, or one of them is nitrogen and the other is CH or an R.sub.4 - or R.sub.5 -substituted carbon atom, have selective receptor agonist or antagonist activity, and are of potential therapeutic utility as analgesics or immunomodulating and/or cardiovascular agents. ##STR1##
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.