Patent · US Expired

(+) and (-)-8-chloro-6-sulfonyloxy-octanoic acid, its derivatives, and methods for making

US5731448A · kind A · utility

3Cited by

0References

11Claims

0Family size

Assignee

Arzneimittelwerk Dresden GmbH · DE

Inventors

Rainer Gewald · Dresden, DE
Gunter Laban · Dresden, DE
Thomas Beisswenger · Radebeul, DE

Key dates

Filing date	Aug 29, 1996
Grant date	Mar 24, 1998
Priority date	—
Expiry date	Aug 29, 2016

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07C319/08
WIPO fieldOrganic fine chemistry
WIPO sectorChemistry

Abstract

The synthesis of pure enantiomers of 8-chloro-6-sulfonyloxy-octanoic acids and their alkyl esters and of pure enantiomers of 6,8-dichloro-octanoic acid and its alkyl esters as intermediates for the synthesis of the enantiomers of .alpha.-liponic acid as well as a method for converting the two enantiomers of 8-chloro-6-hydroxy-octanoic acid into an enantiomer of .alpha.-liponic acid.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.