Allosteric modifiers of hemoglobin useful for decreasing oxygen affinity and preserving oxygen carrying capability of stored blood
US5731454A · kind A · utility
19Cited by
4References
10Claims
0Family size
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Key dates
| Filing date | Jan 18, 1995 |
| Grant date | Mar 24, 1998 |
| Priority date | — |
| Expiry date | Jan 18, 2015 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07C2603/74
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A family of compounds has been found to be useful for right-shifting hemoglobin towards a low oxygen affinity state. The compounds are capable of acting on hemoglobin in whole blood. In addition, the compounds can maintain the oxygen affinity in blood during storage and can restore the oxygen affinity of outdated blood.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.