Transdermal patch for comparative evaluations
US5733571A · kind A · utility
Assignee
Inventor
Key dates
| Filing date | Jan 5, 1996 |
| Grant date | Mar 31, 1998 |
| Priority date | — |
| Expiry date | Jan 5, 2016 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K9/7069
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A transdermal patch useful for evaluating the therapeutic effectiveness of a transdermally delivered medicinal agent is disclosed. The patch includes a substantially impermeable backing layer, a delivery layer containing a medicament and a substantially impermeable blocking layer. The delivery layer is arranged between the backing and blocking layers to prevent the release of the medicament contents from the delivery layer when the transdermal patch is affixed to the skin of a mammal. In alternative embodiments, non-transdermal placebo systems such as oral dosage forms which are coated with substantially impermeable layers to create virtually identical placebos of active oral delivery systems such as tablets, capsules and osmotic tablets are disclosed. Methods of comparing the therapeutic effectiveness of active dosage forms, i.e. transdermal units containing a medicament to placebo or to comparable active agents in either similar or different delivery systems are also disclosed.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.