Complexes of nucleic acid and polymer, their process of preparation and their use for the transfection of cells
US5733762A · kind A · utility
11Cited by
1References
15Claims
0Family size
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Key dates
| Filing date | Oct 31, 1996 |
| Grant date | Mar 31, 1998 |
| Priority date | — |
| Expiry date | Oct 31, 2016 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K47/645
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A compound consisting essentially of polylysine conjugated to non-charged residues and recognition signals wherein the free amino functions of said polylysine are substituted with non-charged residues and said recognition signals, which non-charged residues consist of gluconalactone and which recognition signals are at least one member of the group consisting of galactoside, mannoside, fucoside, Lewis.sup.x, Lewis.sup.b, oligomannoside, oligolactosamine saccharides and peptide ANP and said conjugated polylysine contains at least 30% unsubstituted free amino functions and a method of transfecting cultured cells.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.