Patent · US Expired

Composition comprising coagulation factor VIII formulation, process for its preparation and use of a surfactant as stabilizer

US5733873A · kind A · utility

89Cited by

6References

35Claims

0Family size

Assignee

Pharmacia & UpJohn AB · SE

Inventors

Thomas Österberg · Linköping, SE
Angelica Fatouros · Stockholm, SE

Key dates

Filing date	May 20, 1994
Grant date	Mar 31, 1998
Priority date	—
Expiry date	May 20, 2014

Classification

Technology area (CPC Y)Emerging Cross-Sectional Technologies
CPC primaryY10S530/83
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

A composition comprising coagulation factor VIII and a non-ionic surfactant such as block copolymers, e.g., polyoxamers or polyoxyethylene (20) sorbitan fatty acid esters, e.g., polysorbate 20 or polysorbate 80 as stabilizer is provided. The composition can also comprise sodium chloride, calcium chloride, L-histidine and/or sugars or sugar alcohols.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.