Antiarrythmic and cardioprotective substituted indenoylguanidines

US5733934A · kind A · utility

Assignee

• Hoechst GmbH · DE

Inventors

• Nigrogi Venkata Satya Ramakrishna · Yellandu, IN
• Tulsidas More · Mumbai, IN
• Anagha Suhas Kulkarni · Thane, IN
• Bansi Lal · Yellandu, IN
• Rao Venkata Satya Veerabhadra Vadlamudi · Yellandu, IN
• Anil Ghate · Thane, IN
• Ravindra Dattatraya Gupte · Jamkhed, IN
• Wolfgang Scholz · Beverly, US
• Hans-Jochen Lang · Hofheim, DE

Key dates

• Filing date: Apr 16, 1996
• Grant date: Mar 31, 1998
• Expiry date: Apr 16, 2016

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07C2602/08
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Indenoylguanidines of formula I and formula II, the process for their preparation, their use as medicaments, medicaments containing them, their use as diagnostic agents and medicaments containing them are described. Compounds I are useful for treating cardiac arrhythmias. Further they are useful as cardioprotective agents in mammals, which comprises administering the compound of formula-I or II with the above properties in combination with pharmaceutically accepted carrier to said mammal. ##STR1##