Marker for individuals susceptible to alcoholism
US5736325A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Aug 31, 1994 |
| Grant date | Apr 7, 1998 |
| Priority date | — |
| Expiry date | Aug 31, 2014 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S435/975
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
The present invention relates to methods for diagnosis of susceptibility to alcoholism or the pathological effects of alcoholism based on detection of a genetic marker in an individual. The present invention is directed generally to methods and associated compositions and kits for detecting the presence of arylsulfatase A (ASA) pseudodeficiency (PD) mutations in humans. Detection of these mutations has been surprisingly found to be a strong indicator for susceptibility to alcoholism and/or susceptibility to alcohol's pathological effects, as well as an important marker in evaluating the likelihood of metachromatic leukodystrophy (MLD).
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.