Peptide-enhanced cationic lipid transfections
US5736392A · kind A · utility
154Cited by
5References
34Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jun 4, 1996 |
| Grant date | Apr 7, 1998 |
| Priority date | — |
| Expiry date | Jun 4, 2016 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N15/88
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention discloses compositions useful for transfecting eukaryotic cells comprising nucleic acid complexes with peptides, proteins or protein fragments, wherein the peptide is optionally covalently coupled to a DNA-binding group, and cationic lipids useful for transfecting eukaryotic cells. Methods for the preparation of transfecting compositions and use as intracellular delivery agents and extracellular targeting agents are also disclosed.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.