Peptidase inhibitors
US5736520A · kind A · utility
38Cited by
8References
1Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | May 4, 1995 |
| Grant date | Apr 7, 1998 |
| Priority date | — |
| Expiry date | May 4, 2015 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K38/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
This invention relates to analogs of peptidase substrates in which the nitrogen atom of the scissile amide group of the substrate peptide has been replaced by H, an aldehyde, a substituted carbonyl or a substituted malonyl moiety. These analogs of the peptidase substrates provide specific enzyme inhibitors for a variety of proteases, the inhibition of which will have useful physiological consequences in a variety of disease states.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.