Method for stabilizing proteins with saccharide linked protein polymer conjugates
US5736625A · kind A · utility
108Cited by
11References
17Claims
0Family size
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Key dates
| Filing date | Jun 6, 1995 |
| Grant date | Apr 7, 1998 |
| Priority date | — |
| Expiry date | Jun 6, 2015 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S530/816
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A method is disclosed for preparing water soluble protein polymer conjugates which stabilize the protein so as to retain functional properties in a hostile environment. The method comprises covalently bonding the polymer to the protein through at least three linkers which linkers have three or more hydroxyl groups. The protein is conjugated at lysines or arginines.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.