Methods of enhancing antigen-specific T cell responses
US5738852A · kind A · utility
55Cited by
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15Claims
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Key dates
| Filing date | Jul 29, 1996 |
| Grant date | Apr 14, 1998 |
| Priority date | — |
| Expiry date | Jul 29, 2016 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2740/12043
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Recombinant polynucleotides are provided that confer at least partial immunity on an individual to an infectious intracellular pathogenic agent. The recombinant polynucleotides encode a costimulatory factor and/or a target antigen polypeptide. The immune response that confers the immunity results from the expression of both polypeptides in an antigen presenting cell in the individual. The immunity is to the pathogenic agent that naturally encodes the target antigen polypeptide.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.