2,4'-bridged bis-2,4-diaminoquinazolines

US5739127A · kind A · utility

Assignee

• BAYER HEALTHCARE LLC · DE

Inventors

• Rudolf Schohe-Loop · Wuppertal, DE
• Peter-Rudolf Seidel · Cologne, DE
• William Bullock · Wuppertal, DE
• Gabriele Handke · Wuppertal, DE
• Achim Feurer · Wilhelmsfeld, DE
• Wolfgang Roben · Bensberg, DE
• Georg Terstappen · Düsseldorf, DE
• Joachim Schuhmacher · Wuppertal, DE
• Franz-Josef van der Staay · Dronten, NL
• Bernard Schmidt · Lindlar, DE
• Richard J. Fanelli · Madison, US
• Jane C. Chisholm · Clinton, US
• Richard T. McCarthy · Madison, US

Key dates

• Filing date: Nov 8, 1996
• Grant date: Apr 14, 1998
• Expiry date: Nov 8, 2016

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D471/04
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

The present invention provides 2,4'-bridged bis-2,4-diaminoquinazolines of the general formula (I): ##STR1## in which the indicated substituents are as defined in the description. The invention also provides a process for the preparation of the compounds of the formula (I), drugs containing said compounds and processes for the preparation of drugs containing said compounds.