Cyclopentane- and -pentene-.beta.-amino acids

US5739160A · kind A · utility

Assignee

• BAYER HEALTHCARE LLC · DE

Inventors

• Joachim Mittendorf · Wuppertal, DE
• Franz Kunisch · Odenthal, DE
• Michael Matzke · Wuppertal, DE
• Hans-Christian Militzer · Odenthal, DE
• Rainer Endermann · Wuppertal, DE
• Karl G. Metzger · Wuppertal, DE
• Klaus-Dieter Bremm · Recklinghausen, DE
• Manfred Plempel · Haan, DE

Key dates

• Filing date: Sep 19, 1994
• Grant date: Apr 14, 1998
• Expiry date: Sep 19, 2014

Classification

• Technology area (CPC Y): Emerging Cross-Sectional Technologies
• CPC primary: Y02P20/55
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

New Cyclopentane- or cyclopentene-beta-aminoacid derivatives and their isomers, acid additional salts and metal salt complexes have strong antimicrobial and broad-spectrum antimycotic acitivity. As antimycotics they are especially active against dermatophyte, and biphasic fungi. The new compounds are also low toxicity antibacterial agents, effective against Gram positive bacteria, including antibiotic-resistant strains. The new Cyclopentane- or cyclopentene-beta-aminoacid derivatives are useful in human or veterinary medicine for combating dermatomycosis or systemic mycosis or local or systemic bacterial infections. In addition, the new compounds can also be used as preservatives, especially for water, foods, or organic materials such as polymers, lubricants, paints, fibers, leather, paper or wood.