Patent · US Expired

Substituted terphenyl compounds for the treatment of inflammation

US5739166A · kind A · utility

10Cited by
9References
47Claims
0Family size

Assignee

Inventors

Key dates

Filing dateNov 29, 1994
Grant dateApr 14, 1998
Priority date
Expiry dateNov 29, 2014

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D319/18
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

A class of terphenyl compounds is described for use in treating inflammation and inflammation-related disorders. Compounds of particular interest are defined by Formula II: ##STR1## wherein each of R.sup.2 and R.sup.3 is independently selected from hydrido and halo; or wherein R.sup.2 and R.sup.3 together form --OCH.sub.2 O--; wherein each of R.sup.6 through R.sup.8 is independently selected from hydrido, lower alkyl, halo, lower alkoxy, lower haloalkyl, and lower dialkylamino; or wherein R.sup.6 and R.sup.7 together form --OCH.sub.2 O; and wherein R.sup.12 is selected from lower alkylsulfonyl and aminosulfonyl; or a pharmaceutically-acceptable salt thereof.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.