Labelling agents comprising boronic acid conjugates
US5739318A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Jul 12, 1993 |
| Grant date | Apr 14, 1998 |
| Priority date | — |
| Expiry date | Jul 12, 2013 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N33/533
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
The present invention relates to labelling agents comprising non-proteinaceous boronic acid conjugates having absorption maxima at not less than 600 nm, said label being provided by e.g., an azine, triphenylmethane, cyanine or phthalocyanine dye. The labelling agents are useful in the estimation and quantification of cisdiols such as glycosylated haemoglobin, by virtue of the substantially total absence of overlap with the absorption spectrum of haemoglobin. Oxazine and thiazine dyes exhibiting similar absorption characteristics and containing other activated moieties are similarly useful labelling agents, especially in the presence of haemoglobin.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.