Patent · US Expired

Process for the preparation of furosemide

US5739361A · kind A · utility

3Cited by

1References

10Claims

0Family size

Assignee

Proteos S.r.L. · IT

Inventors

Angelo Signor · Padova, IT
Alfredo Guerrato · Arzignano, IT
Giovanni Signor · Padova, IT

Key dates

Filing date	Apr 23, 1997
Grant date	Apr 14, 1998
Priority date	—
Expiry date	Apr 23, 2017

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07C17/14
WIPO fieldOrganic fine chemistry
WIPO sectorChemistry

Abstract

A new process for the preparation of furosemide 4-chloro-N-(2-furylmethyl)-5-sulfamoyl-anthranilic acid!comprising the photochlorination of 4-chloro-2-fluoro-toluene to give 4-chloro-2-fluoro-benzotrichloride, the aminosulfonylation of the same and the subsequent condensation with furfurylamine.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.