Combinatorial libraries of labeled biochemical compounds and methods for producing same
US5741713A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Jun 21, 1996 |
| Grant date | Apr 21, 1998 |
| Priority date | — |
| Expiry date | Jun 21, 2016 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K1/047
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Combinatorial libraries of labeled biochemical compounds and methods for producing such combinatorial libraries comprising the steps of producing labeled individual units, combining at least two of the labeled individual units so as to produce a labeled biochemical compound, and repeating this process at least once so as to produce a combinatorial library of labeled biochemical compounds. Also, methods for determining the conformation of a biochemical compound which comprise producing a combinatorial library of labeled biochemical compounds, contacting the combinatorial library of labeled biochemical compounds with a target receptor molecule so that a selected labeled biochemical compound binds to the target receptor molecule, and determining the conformation of the selected labeled biochemical compound when bound to the receptor molecule.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.