Expression of a tumor-specific antigen by a recombinant vector virus and use thereof in preventitive or curative treatment of the corresponding tumor
US5744133A · kind A · utility
23Cited by
1References
26Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Dec 15, 1994 |
| Grant date | Apr 28, 1998 |
| Priority date | — |
| Expiry date | Dec 15, 2014 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY02A50/30
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention concerns a vector being vaccinia virus, which comprises a heterologous DNA sequence which codes at least for the essential region of a tumor specific protein called T antigen, cloned within a non essential region of the vaccinia virus, as well as regulatory element required for the expression of said DNA sequence in higher cells, the vector is particularly useful as a pharmaceutical composition having a preventive or creative activity against tumors especially tumors caused by a papillomavirus.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.