Sustained release formulation of animal growth hormone and process for preparation thereof
US5744163A · kind A · utility
15Cited by
2References
10Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Nov 13, 1996 |
| Grant date | Apr 28, 1998 |
| Priority date | — |
| Expiry date | Nov 13, 2016 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K9/0024
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to a sustained-release formulation of an animal growth hormone and a process for preparation thereof, comprising a step to produce solid pellets by mixing an animal growth hormone and an excipient in accordance with a direct tabletting method and a step to coat the pellets with a film comprising a biodegradable polymer and a poloxamer. The thus obtained formulation has small initial drug release, and shows a continuous and uniform effect when administered. Further, the formulation of the present invention may be produced economically in a large scale.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.