Drug delivery compositions
US5744166A · kind A · utility
Assignee
Inventor
Key dates
| Filing date | Dec 21, 1995 |
| Grant date | Apr 28, 1998 |
| Priority date | — |
| Expiry date | Dec 21, 2015 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K47/61
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Compositions for delivery of pharmacologically active agents and methods for their administration are provided. In one embodiment, the compositions include a complex of a polycationic polymer and a pharmacologically active agent in a pharmaceutically acceptable carrier. The compositions in one embodiment permit transport of pharmacologically active compounds across mucosal membranes for systemic delivery. The polycationic polymer may be, for example, a polycationic carbohydrate such as a chitosan or a chitosan salt or derivative. The therapeutic agent a preferred embodiment is a vaccine or a nucleic acid, such as a gene or antisense oligonucleotide. The composition may be provided in different forms such as a solution, dispersion, powder or in the form of microspheres.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.