Process of transfecting a cell with a polynucleotide mixed with an amphipathic compound and a DNA-binding protein
US5744335A · kind A · utility
129Cited by
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15Claims
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Assignee
Inventors
Key dates
| Filing date | Sep 19, 1995 |
| Grant date | Apr 28, 1998 |
| Priority date | — |
| Expiry date | Sep 19, 2015 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N15/87
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The present invention provides a process of transfecting a cell with a polynucleotide mixed with one or more amphipathic compounds and an effective amount of a DNA-binding protein. Exemplary and preferred DNA-binding proteins are H1, H2A, and H2B. Exemplary and preferred amphipathic compounds are cationic amphipathic compounds.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.