Methods for obtaining production of a gene product in a host cell in vivo or in vitro using a DNA molecule for integration site independent gene expression
US5744456A · kind A · utility
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14Claims
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Key dates
| Filing date | Jun 7, 1995 |
| Grant date | Apr 28, 1998 |
| Priority date | — |
| Expiry date | Jun 7, 2015 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K48/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Vectors for the integration of a gene into the genetic material of a mammalian host cell such that the gene may be expressed by the host cell comprise a promoter and the gene and include a dominant activator sequence capable of eliciting host cell-type restricted, integration site independent, copy number dependent expression of the gene.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.