Process for the production of 1,4,7,10-tetraazacyclododecane and its derivatives

US5744616A · kind A · utility

Assignee

• SCHERING CORPORATION · US

Inventors

• Orlin Petrov · Berlin, DE
• Annette Prelle · Berlin, DE
• Klaus-Dieter Graske · Berlin, DE
• Klaus Nickisch · Berlin, DE
• Bernd Raduchel · Berlin, DE
• Johannes Platzek · Berlin, DE

Key dates

• Filing date: Feb 25, 1997
• Grant date: Apr 28, 1998
• Expiry date: Feb 25, 2017

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D257/02
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

A process for the production of 1,4,7,10-tetraazacyclododecane (cyclene) and its derivatives on an industrial scale comprises cyclotetramerizing of benzylaziridine that is produced in situ.