Process for the preparation of aliphatic imines

US5744642A · kind A · utility

Assignee

• BAYER HEALTHCARE LLC · DE

Inventors

• Reinhard Lantzsch · Leverkusen, DE
• Werner Lindner · Eppstein, DE

Key dates

• Filing date: Feb 24, 1995
• Grant date: Apr 28, 1998
• Expiry date: Feb 24, 2015

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07C249/02
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

The invention relates to a novel process for the preparation of aliphatic imines of the general formula (I): ##STR1## in which R.sup.1 is alkyl, alkenyl, alkinyl, cycloalkyl, cycloalkylalkyl, arylalkyl or heteroarylalkyl, each of which is optionally substituted, and PA1 R.sup.2 is optionally substituted alkyl and characterized in that amines of the general formula (II): EQU R.sup.1 --NH.sub.2 (II) in which PA1 R.sup.1 is as defined above, are reacted with aldehydes of the general formula (III): ##STR2## in which R.sup.2 is as defined above, in the presence of a practically water-immiscible organic solvent, at temperatures between -30.degree. C. and +50.degree. C.