Patent · US Expired

Hybrid slab-microchannel gel electrophoresis system

US5746901A · kind A · utility

36Cited by
5References
19Claims
0Family size

Assignee

Inventors

Key dates

Filing dateApr 5, 1996
Grant dateMay 5, 1998
Priority date
Expiry dateApr 5, 2016

Classification

  • Technology area (CPC G)Physics
  • CPC primaryG01N27/44791
  • WIPO fieldMeasurement
  • WIPO sectorInstruments

Abstract

A hybrid slab-microchannel gel electrophoresis system. The hybrid system permits the fabrication of isolated microchannels for biomolecule separations without imposing the constraint of a totally sealed system. The hybrid system is reusable and ultimately much simpler and less costly to manufacture than a closed channel plate system. The hybrid system incorporates a microslab portion of the separation medium above the microchannels, thus at least substantially reducing the possibility of non-uniform field distribution and breakdown due to uncontrollable leakage. A microslab of the sieving matrix is built into the system by using plastic spacer materials and is used to uniformly couple the top plate with the bottom microchannel plate.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.