Prolonged local anesthesia with colchicine
US5747060A · kind A · utility
268Cited by
30References
33Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Mar 26, 1996 |
| Grant date | May 5, 1998 |
| Priority date | — |
| Expiry date | Mar 26, 2016 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K9/1647
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A formulation for inducing sustained regional local anesthesia in a patient comprising a substrate comprising a local anesthetic and an effective amount of a biocompatible, biodegradable, controlled release material prolonging the release of the local anesthetic from the substrate to obtain a reversible nerve blockade when implanted or injected in a patient, and an amount of colchicine effective to prolong the duration of the local anesthesia for a time period longer than that obtainable from the substrate without colchicine.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.