Determination of peptide motifs on MHC molecules

US5747269A · kind A · utility

Assignee

• Max-Planck-Gesellschaft zur Föderung der Wissenschaften e.V. · US

Inventors

• Hans-Georg Rammensee · Lörrach, DE
• Kirsten Falk · Berlin, DE
• Olaf Rotzschke · Somerville, US
• Stefan Stevanovic · Lörrach, DE
• Gunther Jung · Tübingen, DE

Key dates

• Filing date: May 9, 1994
• Grant date: May 5, 1998
• Expiry date: May 9, 2014

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61K38/00
• WIPO field: Measurement
• WIPO sector: Instruments

Abstract

The present invention concerns a method for the determination of allele-specific peptide motifs on molecules of the major histocompatibility complex (MHC) of classes I and II as well as the peptide motifs which are obtainable by the method according to the invention. In addition the use of the peptide motifs according to the invention for the production of a diagnostic or therapeutic agent is disclosed.