Basophil granule proteins
US5747283A · kind A · utility
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9Claims
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Key dates
| Filing date | Dec 18, 1995 |
| Grant date | May 5, 1998 |
| Priority date | — |
| Expiry date | Dec 18, 2015 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S530/838
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Several natural polypeptides (basophil granule proteins, "BGP") derived from the cytoplasmic granules of human basophils, and modified forms thereof, are described. These polypeptides, the DNA which encodes them and antibodies which recognize them, are useful as diagnostics for, and treatments for, pathologies involving inflammatory and IgE-mediated responses, parasitic and helminthic infections, hypersensitivity reactions and certain types of leukocytic leukemias.
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