Antiviral 2, 4-pyrimidinedione derivatives
US5747500A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Jun 18, 1996 |
| Grant date | May 5, 1998 |
| Priority date | — |
| Expiry date | Jun 18, 2016 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D239/60
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Novel 2,4-pyrimidinedione compounds, and pharmaceutically acceptable salts thereof which possess good antiviral activities, and specifically represented by the following formula(I): ##STR1## wherein: R.sup.1 represents an unsubstituted or substituted allyl group represented by CH.sub.2 CH.dbd.CR.sup.5 R.sup.6 or an unsubstituted or substituted propargyl group represented by CH.sub.2 C.tbd.CR.sup.7 wherein R.sup.5, R.sup.6 and R.sup.7 are each independently a hydrogen atom; a methyl group optionally substituted with a halogen atom, or a C.sub.1-10 carbonyloxy, hydroxy, azido, cyano, optionally substituted amino, optionally substituted phosphonyl, optionally substituted phenyl, C.sub.3-10 heteroaryl, C.sub.1-3 alkoxy or benzyloxy radical; a C.sub.2-10 alkyl or alkenyl group; a cyclopropyl group; an optionally substituted phenyl group; a C.sub.3-10 heteroaryl group; a C.sub.1-10 ester group; or an optionally substituted C.sub.1-10 alkylamide group; PA1 R.sup.2 represents a halogen atom, an optionally substituted C.sub.1-5 alkyl, C.sub.3-6 cycloalkyl, C.sub.2-8 alkenyl, C.sub.2-8 alkynyl group or a benzyl group; PA1 R.sup.3 and R.sup.4 represent independently a hydrogen or halogen atom…
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.