Patent · US Expired

Metalloproteinase inhibitors

US5747514A · kind A · utility

20Cited by
1References
27Claims
0Family size

Assignee

Inventors

Key dates

Filing dateJul 19, 1996
Grant dateMay 5, 1998
Priority date
Expiry dateJul 19, 2016

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D417/12
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

The present invention relates to therapeutically active hydroxamic acid and carboxylic acid derivatives, to processes for their preparation, to pharmaceutical compositions containing them, and to the use of such compounds in medicine. In particular, the compounds are inhibitors of metalloproteinases involved in tissue degradation, and in addition are inhibitors of the release of tumor necrosis factor from cells.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.