Use of hydrophobic interaction chromatography to purify polyethylene glycols
US5747639A · kind A · utility
27Cited by
3References
16Claims
0Family size
Assignee
Inventor
Key dates
| Filing date | Mar 6, 1996 |
| Grant date | May 5, 1998 |
| Priority date | — |
| Expiry date | Mar 6, 2016 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P31/04
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to a process for purifying polyethylene glycols (PEGs) which utilizes hydrophobic interaction chromatography (HIC) to separate the PEGs based on their size and on their end-group functionality. The purified PEGs can be used to modify biologically active molecules and improve overall production of such molecules.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.