Delivery of nucleotides into organisms by electroporation
US5749847A · kind A · utility
75Cited by
20References
49Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jun 6, 1995 |
| Grant date | May 12, 1998 |
| Priority date | — |
| Expiry date | Jun 6, 2015 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61B5/14532
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A method for delivering a nucleotide into an organism includes applying a composition which includes a nucleotide component to epidermis of the organism. The epidermis is electroporated, whereby at least a portion of the composition enters or passes across the epidermis, thereby delivering the nucleotide into the organism. An example of a suitable nucleotide which can be delivered by the method of the invention includes antisense oligodeoxynucleotides for treatment of melanomas.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.