Methods of detecting nucleic acids with nucleotide probes containing 4'-substituted nucleotides and kits therefor
US5750343A · kind A · utility
29Cited by
8References
23Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | May 2, 1995 |
| Grant date | May 12, 1998 |
| Priority date | — |
| Expiry date | May 2, 2015 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07H21/00
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
This invention relates to use of oligonucleotides having at least one nucleotide that is substituted at the 4'-position of the sugar moiety with a substituent other than hydrogen as nucleotide probes in methods for detecting the presence or amount of a polynucleotide analyte in a sample suspected of containing the polynucleotide analyte. These oligonucleotides can also be packaged in diagnostic assay kits.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.