DNA encoding MAGE-1 C-terminal cytotoxic t lymphocyte immunogenic peptides
US5750395A · kind A · utility
35Cited by
3References
3Claims
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Key dates
| Filing date | Jun 5, 1995 |
| Grant date | May 12, 1998 |
| Priority date | — |
| Expiry date | Jun 5, 2015 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K39/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The complete nucleotide and amino acid sequences of the human MAGE-1 antigen are provided. Peptides from residues of the C-terminal are used to define epitopes that stimulate HLA-restricted cytotoxic T lymphocyte activity against MAGE-1 antigens. The peptides are particularly useful in methods for stimulating the immune response of individuals against MAGE-1 antigens associated with melanomas.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.