Stable virus packaging cell lines
US5750396A · kind A · utility
14Cited by
0References
27Claims
0Family size
Assignees
Inventors
Key dates
| Filing date | May 8, 1995 |
| Grant date | May 12, 1998 |
| Priority date | — |
| Expiry date | May 8, 2015 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2760/20222
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The field of the invention is recombinant packaging and producer cell lines for producing infectious retroviral vectors. The invention more specifically relates to the generation of pseudotyped retroviral vectors with a broad host range which can be produced at high titers in specially constructed packaging cell lines. Most specifically, the invention relates to the generation of pseudotyped retroviral vectors having vesicular stomatitis virus-G protein (VSV-G) as the membrane-associated viral envelope protein.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.