Patent · US Expired

Dihydrobenzofuran and related compounds useful as anti-inflammatory agents

US5750543A · kind A · utility

0Cited by
3References
13Claims
0Family size

Assignee

Inventors

Key dates

Filing dateFeb 1, 1996
Grant dateMay 12, 1998
Priority date
Expiry dateFeb 1, 2016

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D417/06
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

A compound having the structure: ##STR1## wherein (a) n is from 1 to about 3; PA1 (b) X is selected from the group consisting of O, S, SO, or SO.sub.2 ; PA1 (c) Y is independently hydrogen or straight, branched or cyclic alkyl having from 1 to about 4 carbon atoms, or the Y's are bonded together to form an alkanyl ring having from about 3 to about 7 atoms; PA1 (d) Z is hydrogen or straight, branched or cyclic alkyl having from 3 to about 10 atoms other than hydrogen; PA1 (e) W is O or S; and PA1 (f) Het is a heteroaryl group comprising one or more rings each ring containing from about 5 to about 6 atoms other than hydrogen and wherein the group contains at least one heteroatom selected from O, N, or S. pharmaceutical compositions comprising such compounds, and methods of treating inflammation or pain using such compounds.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.