Nucleosides with 2'-O-modifications
US5750673A · kind A · utility
33Cited by
1References
9Claims
0Family size
Assignee
Inventor
Key dates
| Filing date | Apr 20, 1995 |
| Grant date | May 12, 1998 |
| Priority date | — |
| Expiry date | Apr 20, 2015 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY02P20/55
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Compounds of the formula ##STR1## wherein R.sub.1 and R.sub.2 are each independently of the other hydrogen or a protecting group, or R.sub.1 has those meanings and R.sub.2 is a radical forming a phosphorus-containing nucleotide bridge group; B is a purine or pyrimidine radical or an analogue thereof; and R.sub.3 is OH, F or (CF.sub.2).sub.n CF.sub.3 wherein n is a number from 0 to 7, and oligonucleotides that comprise those nucleosides are described.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.