Patent · US Expired

1,3-dimethyl-5-fluoro-pyrazole-4-carbonyl fluoride

US5750721A · kind A · utility

4Cited by

3References

1Claims

0Family size

Assignee

BAYER HEALTHCARE LLC · DE

Inventors

Bernd Gallenkamp · Wuppertal, DE
Lothar Rohe
Albrecht Marhold · Leverkusen, DE

Key dates

Filing date	Apr 9, 1997
Grant date	May 12, 1998
Priority date	—
Expiry date	Apr 9, 2017

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07D231/14
WIPO fieldOrganic fine chemistry
WIPO sectorChemistry

Abstract

A new process for the preparation of a known 1,3-dimethyl-5-fluoro-pyrazole-4-carboxanilide of the formula ##STR1## in which Ar represents optionally substituted phenyl, which process comprises PA1 a) reacting in a first stage, 1,3-dimethyl-5-chloro-pyrazole-4-carbonyl chloride with a fluoride, if appropriate in the presence of a diluent, and PA1 b) reacting in a second stage, the 1,3-dimethyl-5-fluoro-pyrazole-4-carbonyl fluoride obtained in this reaction with an aniline of the formula EQU H.sub.2 N--Ar in which PA1 Ar has the abovementioned meaning, PA1 if appropriate in the presence of an acid acceptor and if appropriate in the presence of a diluent. 1,3-Dimethyl-5-fluoro-pyrazole-4-carbonyl fluoride as a new compound.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.