Positive correlation filter systems and methods of use thereof
US5750994A · kind A · utility
Assignee
Inventor
Key dates
| Filing date | Oct 24, 1995 |
| Grant date | May 12, 1998 |
| Priority date | — |
| Expiry date | Oct 24, 2015 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N21/359
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
A number of optically active elements are provided that enable the performance of accurate, dependable chemical analysis in a medium having varying matrix backgrounds and substantial component interferences. Optical transfer cells are provided that include positive correlation filter systems adapted to accept near-IR radiation and to pass a wavelength from that radiation having high correlation with a particular analyte. A near-IR spectrometer apparatus for the measurement of analyte concentration in a complex medium is also provided. The apparatus features an optical transfer cell constructed according to the invention. The apparatus can be used in the non-invasive determination of blood analyte concentrations in a variety of mediums. Methods of measuring the concentration of a blood analyte in a mammalian subject are also provided. The methods entail the use of reflective near-IR radiation to interrogate a medium to obtain spectrally modified radiation. The radiation thus obtained is passed through an optical transfer cell constructed according to the invention to obtain a wavelength having high correlation with an analyte of interest and substantially no correlation with interfe…
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.