Syringe and method for lyophilizing and reconstituting injectable medication
US5752940A · kind A · utility
Assignee
Inventor
Key dates
| Filing date | Apr 8, 1996 |
| Grant date | May 19, 1998 |
| Priority date | — |
| Expiry date | Apr 8, 2016 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61M2005/3121
- WIPO fieldMedical technology
- WIPO sectorInstruments
Abstract
A syringe assembly includes a substantially cylindrical syringe barrel and a plunger stopper. Distal portions on the plunger stopper are configured to permit outflow of vapor from the syringe barrel during a lyophilization process. Proximal portions of the plunger stopper are dimensioned to engage the syringe barrel in sliding fluid-tight engagement. Liquid medication in the chamber is lyophilized and a vacuum is applied to the syringe barrel after lyophilization. The plunger stopper then is urged distally into sealing engagement with the syringe barrel. A plunger rod can be engaged with the plunger stopper. The tip cap is then removed and a diluent is drawn into the chamber by moving the plunger rod and the plunger stopper in a proximal direction. The syringe assembly then can be used in the standard manner.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.