Viral vector complexes having adapters of predefined valence
US5753499A · kind A · utility
10Cited by
1References
29Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Dec 23, 1994 |
| Grant date | May 19, 1998 |
| Priority date | — |
| Expiry date | Dec 23, 2014 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2740/10043
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The invention concerns an improvement in the art of inserting and expressing foreign gene into eukaryotic cells. The invention particularly concerns methods and compositions whereby viral vectors can be used to insert and express foreign genes into specifically cells having particular differentiation antigens. A method of determining which differentiation antigens can be used is taught. The invention encompasses complexes of viral particles and adapters that cause the binding and internalization of the vector particles such that a gene of interest in the particle is expressed.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.