Composition for prophylaxis or treatment of pulmonary circulatory diseases
US5753619A · kind A · utility
2Cited by
0References
15Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Nov 29, 1995 |
| Grant date | May 19, 1998 |
| Priority date | — |
| Expiry date | Nov 29, 2015 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K38/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Cyclic hexapeptides having antagonistic activity on endothelin receptors of the formula I!: ##STR1## wherein X and Y each is an .alpha.-amino acid residue having D-, L-form or DL-form, A is a D-acidic-.alpha.-amino acid residue, B is a neutral-.alpha.-amino acid residue having D- or L-form, C is an L-.alpha.-amino acid residue and E is a D-.alpha.-amino acid residue having an aromatic ring group can be effectively used for prophylaxis and/or treatment of pulmonary circulatory diseases.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.