Patent · US Expired

Adenosine diphosphoribose polymerase binding nitroso aromatic compounds useful as retroviral inactivating agents, anti-retroviral agents, anti-retroviral agents and anti-tumor agents

US5753674A · kind A · utility

25Cited by
1References
10Claims
0Family size

Assignee

Inventors

Key dates

Filing dateJun 7, 1995
Grant dateMay 19, 1998
Priority date
Expiry dateJun 7, 2015

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D311/18
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

The subject invention provides for novel compounds for inactivating viruses. These compounds include 6-nitroso-1,2-benzopyrone, 3-nitrosobenzamide, 5-nitroso-1 (2H)-isoquinolinone, 7-nitroso-1(2H)-isoquinolinone, 8-nitroso-1 (2H)-isoquinolinone. The invention also provides for compositions containing one or more of the compounds, and for methods of treating viral infections, cancer, infectious virus concentration with the subject compounds and compositions.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.