Patent · US Expired

Angled chamber seal for atmospheric pressure ionization mass spectrometry

US5753910A · kind A · utility

50Cited by
5References
26Claims
0Family size

Assignee

Inventors

Key dates

Filing dateJul 12, 1996
Grant dateMay 19, 1998
Priority date
Expiry dateJul 12, 2016

Classification

  • Technology area (CPC G)Physics
  • CPC primaryG01N30/7266
  • WIPO fieldMeasurement
  • WIPO sectorInstruments

Abstract

An atmospheric pressure ionization source is provided which includes an ionization chamber that is formed from the combination of an angled chamber body and a correspondingly angled chamber seal. The ionization chamber is used for electrospray or atmospheric pressure chemical ionization of a liquid sample to provide ionized molecules. The ionized molecules can be passed to an associated analytical device that is capable of detecting and measuring the mass-to-charge ratio and/or the mass and charge of the molecules. A mass spectrometer which includes the present atmospheric pressure ionization source is also provided, as well as a liquid chromatography/mass spectrometry (LC/MS) analysis system which includes an LC/MS interface comprising the present atmospheric pressure ionization source.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.